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Courses » Stereochemistry

Stereochemistry

ABOUT THE COURSE
Stereochemistry of molecules dictates isomerism, chemical and biochemical reactivity. Reactivity. These days, chiral drugs have become an integral part of pharmaceutical industry. A basic concept on 3D structures and conformations of molecules and asymmetric synthesis and other stereochemical principles and attributes are essential. This course will lay the foundation on to which further advanced topics can be built up.

Important For Certification/Credit Transfer:

Weekly Assignments and Discussion Forum can be accessed ONLY by enrolling here

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Note: Content is Free!

All content including discussion forum and assignments, is free


Final Exam (in-person, invigilated, currently conducted in India) is mandatory for Certification and has INR Rs. 1100 as exam fee



INTENDED AUDIENCE
  • Chemistry
  • Biotechnology
  • Bioscience
  • Pharmacy

PRE-REQUISITES 
+12 Chemistry

INDUSTRY SUPPORT – LIST OF COMPANIES/INDUSTRY THAT WILL RECOGNIZE/VALUE THIS ONLINE COURSE

  • Pharmaceutical industries
  • Perfumery Industries

1302 students have enrolled already!!

COURSE INSTRUCTOR 

Prof. Amit Basa  offering this course at the first year level at IIT Kharagpur for many years. Before that, I had taught UG students of Presidency University for more than 10 years. Due to my interaction with Sir Prof J. Baldwin (my PhD supervisor at Oxford) and Prof Talapatra ( PhD supervisor, both of whom are renowned stereochemists, my interest in teaching stereochemistry at UG and PG level grew up immensely. 
COURSE LAYOUT

Week 1: Constitution and Configuration; Chemistry in 3D space Chirality and its origin, symmetry criterion; 
Week 2: Stereogenicity and topicity; Enantiomers, Diastereomers, Epimers, Anomers, Atropisomers
Week 3: Nomenclature: Absolute (R/S and D,L) and relative configurations (Threo/erythro , syn/anti and like/unlike)
Week 4: Prochirality, pro-R and pro-S designations; related problems
Week 5: Conformations of acyclic systems: X-CH2-CH2-X and of cyclic systems: cyclopropane, cyclobutane, cyclopentane
Week 6: Conformations of cyclohexane (including mono and disubstituted), cis and trans-decalins
Week 7: Stereoelectronic and steric principles in reactions: Substitution, elimination and addition; selectivity and specificity
Week 8: Stereoelectronic and steric principles in reactions: Substitution, elimination and addition; selectivity and specificity (contd); Importance of stereochemistry in real life: some examples

SUGGESTED READING

1. Stereochemistry by Eliel

2. Stereochemistry by Nasipuri

3. Organic Chemistry by Clayden et. al.


CERTIFiCATION EXAM :
  • The exam is optional for a fee.
  • Date and Time of Exam: October 7, 2018 (Sunday)
  • Time of Exams: Morning session 9am to 12 noon; Afternoon session: 2pm to 5pm.
  • Exam for this Course will be available in both morning & afternoon sessions.
  • Registration url: Announcements will be made when the registration form is open for registrations.
  • The online registration form has to be filled and the certification exam fee needs to be paid. More details will be made available when the exam registration form is published.
CERTIFICATE:
  • Final score will be calculated as : 25% assignment score + 75% final exam score
  • 25% assignment score is calculated as 25% of average of 8 weeks course: Best 6 out of 8 assignments
  • E-Certificate will be given to those who register and write the exam and score greater than or equal to 40% final score. Certificate will have your name, photograph and the score in the final exam with the breakup. It will have the logos of NPTEL and IIT Kharagpur. It will be e-verifiable atnptel.ac.in/noc.