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Courses » Biomaterials for bone tissue engineering applications

Biomaterials for bone tissue engineering applications

ABOUT THE COURSE

Biomaterials, recognized as a new class of materials in the Materials Science community, are being developed in last few decades for human health care. The design and development of biomaterials requires the integration of the concepts and expertise from two widely different disciplines, i.e. Materials Science & Engineering and Biological Science. The importance of the field of biomaterials is increasingly being noticed in the Materials community with the compulsory course on this subject is being taught at undergraduate and graduate level in most of the top universities around the world. In India, a compulsory course on biomaterials is being kept in the new course curriculum of undergraduate students in Department of Materials Science and Engineering at IIT Kanpur, while this instructor has taught a more elaborate course on biomaterials for the graduate students at IIT Kanpur and at IISc, Bangalore, over last one decade. This NPTEL course on “Biomaterials for Bone Tissue Engineering applications” will consist of several lectures on the basics of the cell biology and biomaterials science, followed by some case studies, illustrating various aspects of biomaterials development for orthopedic applications. The layout of this lecture series in terms of the succession of various concepts will primarily facilitate easier understanding for students and this important area of societal relevance in terms of human healthcare.


INTENDED AUDIENCE

Students of BE/ME/MSc/PhD streams


INDUSTRY SUPPORT – LIST OF COMPANIES/INDUSTRY THAT WILL RECOGNIZE/VALUE THIS ONLINE COURSE

Smith & Nephew/Adler Mediequip Pvt. Ltd., Pune, CIPET, Chennai

664 students have enrolled already!!

COURSE INSTRUCTOR



Dr. Bikramjit Basu is currently a full Professor at the Materials Research Center and holds Associate Faculty position at Center for Biosystems Science and Engineering, Indian Institute of Science (IISc), Bangalore. He is currently an Adjunct faculty at Indian Institute of Technology Kanpur (IITK). After his undergraduate and postgraduate degree in Metallurgical Engineering, he earned his PhD in Ceramics at Katholieke Universiteit Leuven, Belgium in March, 2001. After a brief post-doctoral stint at University of California, Santa Barbara; he joined IITK in November 2001 as Assistant Professor and was promoted to full Professor at IITK in March, 2012. Prof. Basu’s international standing and impact on the field are illustrated by his prolific publication record (more than 225 peer-reviewed journal articles, including 30 papers in journals with high impact factor (>4.0), more than 20 invited review papers/book chapters) and citation record (total citation: ~ 5,300, H-index: 41). He currently serves on editorial board of 12 SCI journals. Dr. Basu has served as a research adviser to 16 PhD students, 20 Masters students and mentored 10 young academic colleagues.

Prof. Basu’s contributions in Engineering Science have been widely recognised. He is one of the youngest recipients from the Metallurgy/Materials Science community as well as the only Biomaterial Scientist so far to receive India’s most coveted science award, Shanti Swarup Bhatnagar award (2013). He is an elected Fellow of the Indian National Academy of Engineering (2015), West Bengal Academy of Science and Technology (2014), Society for Biomaterials and Artificial Organs (2014) and National Academy of Sciences, India (2013). In 2015, he received National Bioscience award from the Government of India for unique contributions in the frontier areas of biological sciences. He remains the only Indian from India to receive the prestigious ‘Coble Award for Young Scholars’ (2008) from the American Ceramic Society.
COURSE LAYOUT

Week 1: Introduction to Biomaterials and Biocompatibility

M1-Introduction, M2-Biomaterial, M3-Biocompatibility, M4- Host response

 

Week 2: Defining tissue engineering scaffolds and implants

M5-Tissue Eng, M6-Scaffold, M14-Bone structure, M15-Bone properties, M16-Implant-I, M17-Implant-II 

 

Week 3: Structure and Properties of Proteins and Cells

M7-Proteins, M8-Cell structure, M13-Bacteria structure, M27-Antibacterial assay

 

Week 4: Stem cells and Cell fate processes

M11-Cell fate processes, M12-Cell division, M23-Cell differentiation, M24-Stem cells

 

Week 5: Cell-material Interaction (in vitro and in vivo) and Clinical trials

M18-Osseointegration, M19-in vivo testing, M9-Cell-material interaction, M10-Cell-signalling, M21-in vitro testing, M22-Cytotoxicity assays, M25-Clinical trials I, M26-Clinical trials II

 

Week 6: Manufacturing of Biomaterials (metals, ceramics and polymers)

M28-Metal manufacturing, M29-Ceramics manufacturing, M30- Polymers manufacturing, M31-Additive manufacturing

 

Week 7: HA-based composites
M32-HA-Ti-Toughness, Cell functionality, M33-HA-CaTiO3 development, M34-HA-BaTiO3 Functional Prop, M35-HA-Ag antimicrob & cell viability, M36-HA-ZnO, Cell fate & antimicrobial

 

Week 8: Glass ceramics for orthopedic and dental applications, acetabular socket and femoral head, prototype development

M37-Dental ceramics: processing, M38-Sr-based glass Ceramics, M39-Acetabular socket (Compression mold), M40-ZTA femoral ball head fabrication



SUGGESTED READING
  1. B. Basu, D. Katti and Ashok Kumar; Advanced Biomaterials: Fundamentals, Processing and Applications; John Wiley & Sons, Inc., USA (ISBN: 978-0-470-19340-2), September, 2009.
  2. Biomaterials Science: An introduction to Materials in Medicine, Edited by Ratner, Hoffman, Schoet and Lemons, Second Edition: Elsevier Academic Press, 2004.
  3. Biomaterials Science and Biocompatability, Fredrick H. Silver and David L. Christiansen, Piscataway, Springer, New Jersey.
  4. Biological Performance of Materials: Fundamentals of Biocompatibility, Janathan Black, Marcel Dekker, Inc., New York and Basel, 1981

MORE DETAILS ABOUT THE COURSE
Course url: https://onlinecourses.nptel.ac.in/noc16_mm09 
Course duration : 8 weeks
Start date and end date of course:18 July 2016 - 9 September 2016
Dates of exams : 18 Sep 2016 & 25 Sep 2016
Time of exam : 2pm - 5pm
Final List of exam cities will be available in exam registration form.
Exam registration url - Will be announced shortly
Exam Fee: The online registration form has to be filled and the certification exam fee of approximately Rs 1000 needs to be paid.

CERTIFICATE

E-Certificate will be given to those who register and write the exam. Certificate will have your name, photograph and the score in the final exam. It will have the logos of NPTEL and Indian Institute of Science, Bangalore

It will be e-verifiable at nptel.ac.in/noc.