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Courses » Human Molecular Genetics

Human Molecular Genetics

ABOUT THE COURSE
 This is an introductory course designed primarily for students in the undergraduate or master’s programs interested in biomedical research, genetic counseling, medicine, and clinical genetics. This course is expected introduce the rapid advancements in our understanding the role of human genome in health and disease. We would introduce key concepts of inheritance of human traits, pedigree analysis, and chromosome organization. Molecular biology tools used for understanding the genome, gene structure and gene mutations, gene mapping and gene cloning strategies will also be covered. Objectives and outcome of human genome project and the HapMap project will also be discussed at the end.

INTENDED AUDIENCE

  • Students interested in pursuing research in human molecular genetics.
  • Medical students and practicing clinicians interested in understanding the principles and complexities of human genetics.
  • Students interested in careers in genetic counselling and DNA diagnostics.
  • Scientists working in public health service, counselling centres, and diagnostic laboratories.

PRE-REQUISITES
Participants are expected to have at least class 12 level understanding in genetics.

INDUSTRIES THAT WILL RECOGNIZE THIS COURSE
 Medical and pharma companies, paramedic clinical centers, educational institutes, and hospitals

650 students have enrolled already!!

COURSE INSTRUCTOR


Prof. S. Ganesh  teaches biology, genetics and human molecular genetics at IIT Kanpur. His research interests include human molecular genetics and neuroscience. He works on genetic forms of neurodegenerative disorders in humans to understand their genetics and disease mechanisms, and to develop therapeutics.  

For details see: http://home.iitk.ac.in/~sganesh/ 

COURSE LAYOUT

Week 1: [2 hrs; 4 x 30 min]
Fundamentals of central dogma (DNA, RNA and proteins; mutations)
Chromosome structure and function (organization; structure-function relationship; chromosome abnormalities)

Week 2: [3 hrs; 6 x 30 min]
Genes in pedigree (Mendelian pedigree patterns, complications to pedigree patterns)
DNA cloning and hybridization techniques (vector based cloning; nuclei acid hybridizations; PCR-based DNA analyses)

Week 3: [2 hrs: 6 x 20 min]
Mutation and instability of human DNA (mutation and polymorphism; pathogenic mutations, repeat expansions)
Molecular pathology (types of mutations; animal models for human disease)

Week 4: [3 hrs: 6 x 20 min]
Identifying human disease genes (functional cloning versus positional cloning; mutation screening)
Complex diseases; The Human Genome and HapMap projects

Certification Exam

The exam is optional. Exams will be on 24 April 2016 and 30 April 2016.
Time: 2pm-5pm

Tentative list of exam cities: http://nptel.ac.in/noc/pdf/Exam%20City-list.pdf

Registration url: Announcements will be made when the registration form is open for registrations.

The online registration form has to be filled and the certification exam fee of approximately Rs 1000 needs to be paid.

Certificate

Certificate will be given to those who register and write the exam. Certificate will have your name, photograph and the score in the final exam.

It will have the logos of NPTEL and IIT Kanpur. It will be e-verifiable at nptel.ac.in/noc.

SUGGESTED READING

1.    “Human Molecular Genetics 4 Tom Strachan, Andrew P. Read Garland Science/Taylor & Francis Group, 2011